Survival of HT29 Cancer Cells Is Affected by IGF1R Inhibition via Modulation of Self-DNA-Triggered TLR9 Signaling and the Autophagy Response
Ferenc Sipos, et al.
Introduction Insulin-like growth factor 1 receptor (IGF1R), a transmembrane protein belonging to the receptor tyrosine kinase family, consists of two subunits (i.e., IGF1R-α and IGF1R-β). IGF1R ligands include insulin and…