Tag: extension

Protocol paper: a multi-center, double-blinded, randomized, 6-month, placebo-controlled study followed by 12-month open label extension to evaluate the safety and efficacy of Saracatinib in Fibrodysplasia Ossificans Progressiva (STOPFOP) – BMC Musculoskeletal Disorders

Study design This phase 2a study is designed as a European multicentre 6-month double blind randomized controlled trial (RCT) of AZD0530 versus placebo, followed by a 12 month open-label extension phase.…

Medial meniscus extrusion and varus tilt of joint line convergence angle increase stress in the medial compartment of the knee joint in the knee extension position -finite element analysis- – Journal of Experimental Orthopaedics

Stress changes in the medial compartment This study revealed that the MME is associated with increased stress loading on the medial compartment structures (femoral and tibial cartilage and meniscus), and…