Tag: Hematology

Novel treatment combining antiviral and neutralizing antibody-based therapies with monitoring of spike-specific antibody and viral load for immunocompromised patients with persistent COVID-19 infection – Experimental Hematology & Oncology

Moran E, Cook T, Goodman AL, Gupta RK, Jolles S, Menon DK, et al. Persistent SARS-CoV-2 infection: the urgent need for access to treatment and trials. Lancet Infect Dis. 2021;21:1345–7.…

Hypoxia-induced exosomal circPDK1 promotes pancreatic cancer glycolysis via c-myc activation by modulating miR-628-3p/BPTF axis and degrading BIN1 – Journal of Hematology & Oncology

Exosomes derived from hypoxia PC cells promote the malignant biological behavior of PC cells in vitro Hypoxia is an important characteristic of pancreatic cancer. Primary tumors with PO2 < 10 mmHg in patients…

Somatic copy number alteration and fragmentation analysis in circulating tumor DNA for cancer screening and treatment monitoring in colorectal cancer patients – Journal of Hematology & Oncology

Tumor-specific global fragmentation pattern To establish a comprehensive data set for LB analysis in all stages of CRC, we applied WGS with a median coverage of 6x (SD = 2.37) in 259…