Tag: instillation

Two-year intermittent exposure of a multiwalled carbon nanotube by intratracheal instillation induces lung tumors and pleural mesotheliomas in F344 rats – Particle and Fibre Toxicology

Preparation of the test material The MWCNT, MWNT-7 (also called as Mitsui-7, XRNI-7, or MWCNT-7; lot, 060 125-01 k), was obtained from Mitsui Chemicals (Tokyo, Japan) and was fully characterized in…

Efficacy of instillation of MB49 cells and thermoreversible polymeric gel in urothelial bladder carcinoma immunization – Laboratory Animal Research

Preparation of thermoreversible polymeric gel (TPG) The delivery system proposed for intravesical inoculation together with MB49 cells consists of a binary polymeric system (Fig. 1) composed of poloxamer 407 (Sigma-Aldrich, St.…

Inflammogenic effect of polyacrylic acid in rat lung following intratracheal instillation – Particle and Fibre Toxicology

Sample polymer CL-PAA (306223 Poly (acrylic acid)®): average Mv ~ 3,000,000) (Sigma-Aldrich Co. LLC., St. Louis, MO, USA) was used. The polymer was mixed with distilled water, slowly stirred for 40 min (Mag-Mixer…