Tag: Intervertebral

Excessive mechanical stress-induced intervertebral disc degeneration is related to Piezo1 overexpression triggering the imbalance of autophagy/apoptosis in human nucleus pulpous – Arthritis Research & Therapy

Tissue samples collection Cervical NP samples were collected through anterior cervical decompression surgery from 20 patients (eight men and twelve women; age range: 35–65 years) with cervical myelopathy or radiculopathy due…

Comparative study of the efficacy and safety of minimally invasive interlaminar full-endoscopic discectomy versus conventional microscopic discectomy in single-level lumbar herniated intervertebral disc (ENDO-F Trial): a multicenter, prospective, randomized controlled trial protocol – Journal of Orthopaedic Surgery and Research

Trial design This study aims to evaluate the non-inferiority of the outcomes of interlaminar full-endoscopic discectomy versus those of microscopic discectomy using a multicenter RCT design. Our methods have been…

Icariin regulates stem cell migration for endogenous repair of intervertebral disc degeneration by increasing the expression of chemotactic cytokines – BMC Complementary Medicine and Therapies

Isolation and identification of ISN-SCs ISN-SCs were separated from 3-month-old male Wister rats (320–380 g, Guangdong Experimental Animal Center) according to the following procedure. The rats were euthanized after intraperitoneal injection…