Introduction Cigarette smoking is one of the leading preventable causes of related chronic diseases and deaths worldwide (1). Nicotine is the main psychoactive component of tobacco that affects many neurotransmitter…

Introduction Whether it is a wedding, college graduation, birth of a child, or death of a loved one, subjectively arousing experiences tend to be better remembered than neutral ones. Such…

Area of study The study was conducted in three rural communities (Obollo-afor, Ezimo-Ulo and Orba) in Udenu LGA, Enugu North senatorial zone of Enugu state, South-east Nigeria. The LGA is…

Introduction The tumor microenvironment (TME) consists of tumor cells, stromal cells, and immune cells, as well as non-cellular components such as chemokines. The striking advance in tumor biology demonstrates that…

Introduction In the last few decades, most low- and middle-income countries (LMIC) have been experiencing rapid socioeconomic development, accompanied by a wide and abrupt increase in urban agglomerations and industrialization…

1. Introduction Brain transplantation of cell-derived cortical pyramidal neurons into the mouse cortex makes for a mouse/human chimera model that helps in the study of human brain development (Linaro et…

Bacterial strain, growth conditions, and inoculum preparation The standard strain S. pullorum ATCC 13036 was obtained from the China Institute of Veterinary Drug Control. The strain was revived on xylose…

Introduction Osteoarthritis (OA) is a degenerative multifactorial disease that is characterized by progressive joint failure, which is often associated with joint pain, stiffness, and decreased range of motion (Lopes et…

Key Points • This study systematically evaluated the modification patterns of 23 m6A regulatory factors in STAD. • This study revealed that m6A modification is significantly associated with TME diversity…

Introduction Bladder cancer (BLCA) is the world’s 10th most prevalent cancer, accounting for around 549,000 new cases and 200,000 deaths in 2018 (Bray et al., 2018). As a highly heterogeneous…