Introduction Tibetan sheep are the most economically important domestic animals on the Qinghai-Tibetan Plateau (QTP), providing native Tibetan herders with meat, wool and milk (1). On the QTP, Tibetan sheep…

Introduction Although Candida albicans is frequently associated with the human host as a commensal, reductions in host immune defense or microbiota can result in the fungus overgrowing its niche and…

Introduction In Western countries, there is an ongoing trend toward plant-based diets, which tend to favor plant protein for replacing animal sources for sustainability reasons, including health and environmental impacts…

Introduction With advances in protein design methods, whole protein design using both naturally occurring and computationally designed protein scaffolds has become common (Pokala and Handel, 2001; Kuhlman and Bradley, 2019).…

Introduction Bacillus subtilis is a non-pathogenic transitional microorganism of the digestive tract (1). When fed to cows, B. subtilis can improve ruminal fermentation and produce various enzymes to promote digestion…

Subjects Nine healthy young Japanese subjects (seven females and two males; age, 22 ± 3 years; height, 162 ± 5 cm; weight, 56 ± 6 kg; mean ± SD) participated in this study. The subjects were normotensive, did not smoke or…

Animals Three-month-old C57BL/6J male mice (Jackson Laboratory) were used for this study. The mice were housed on a 12-h light–dark cycle with ad libitum access to food and water. All…

Yousef H, Morgenthaler A, Schlesinger C, Bugaj L, Conboy IM, Schaffer DV. Age-associated increase in BMP signaling inhibits hippocampal neurogenesis. Stem Cells. 2015;33:1577–88. CAS  PubMed  PubMed Central  Google Scholar  Crews…

Introduction COVID-19, an inflammatory disease state, is associated with significantly elevated systemic inflammatory markers (1–3). COVID-19 has also been associated with an increased risk of cardiac arrhythmias, including life-threatening arrhythmias…

Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185…